How a cancer drug leads to diabetes
Rapamycin is a widely used drug for cancer and transplant patients, and there are hints that it might even help us put off old age and live longer. But, it also comes with a downside: rapamycin leads...
View ArticleHarmless human virus may boost the effects of chemotherapy
A harmless virus may be able to boost the effects of two standard chemotherapy drugs. RT3D, trade name Reolysin, is a new drug developed by Oncolytics Biotech. It is based on a virus (reovirus type 3...
View ArticleResearchers develop new model of inflammatory breast cancer
Researchers have developed a new cell and animal model of inflammatory breast cancer (IBC), a very aggressive form of the disease that is diagnosed more frequently in younger women compared with other...
View ArticleVaccine shows promising survival rates for patients with lung cancer
A long-term follow-up of a clinical trial has shown promising results for patients with non-small cell lung cancer (NSCLC). The findings, presented at the American Association for Cancer Research...
View ArticleScientists discover that no two tumors of deadliest form of breast cancer are...
An international team of scientists mapped the genomes of 100 triple negative breast cancer tumors, the deadliest form of the disease, and discovered that no two genomes were similar. “Seeing these...
View ArticleTargeted nanoparticles show success in first human clinical trials
Targeted therapeutic nanoparticles that accumulate in tumors while bypassing healthy cells have shown promising results in an ongoing clinical trial, according to a new paper. The nanoparticles...
View ArticleNew method for detecting oral cancer
Ninety percent of head and neck cancer cases are due to squamous cell carcinoma -- a cancer of the epithelial cells. Oral squamous cell carcinoma (OSCC) affects 270,000 people worldwide every year,...
View ArticleNewly developed nanostars deliver drugs directly to cancer cell's nucleus
Northwestern University scientists have developed a specialized nanoparticle, called nanostars, that can deliver a drug directly to a cancer cell’s nucleus. The nanoparticle is made of gold and shaped...
View ArticleBreast cancer's fingerprint detectable in blood
A new microfluidics-based microarray developed by a team at McGill University could potentially change how and when cancer is diagnosed. The group measured the profile of 32 proteins in the blood of...
View ArticleRemoving âgood cholesterolâ receptor may protect against breast cancer
Studies conducted at Thomas Jefferson University’s Kimmel Cancer Center have revealed that removing a lipoprotein receptor known as SR-BI may help protect against breast cancer. In an in vitro study,...
View ArticleNanotube thermal therapy kills breast cancer cells
A new study reports that breast cancer stem cells (BCSCs), the slow-growing malignant cells thought to be responsible for the growth and spread of breast cancer that are very resistant to traditional...
View ArticleScientists identify major source of cells' defense against oxidative stress,...
Both radiation and many forms of chemotherapy try to kill tumors by causing oxidative stress in their cells. New research from the University of Southern California (USC) on a protein that protects...
View ArticleGene-targeting pharmaceutical lessens side effects of chemotherapy
The highly-studied, human p53 gene is known to play a key role in cellular stress response mechanisms by converting a variety of different stimuli into cell growth arrest or apoptosis (cell death)....
View ArticleOne step closer to using aspirin to prevent cancer
Recent research has shown that daily aspirin use can prevent cancer, and now a new report by American Cancer Society scientists says that this growing body of data brings us considerably closer to the...
View ArticleResearcher identify protein associated with metastases of breast cancer to...
Researchers at Bellvitge Biomedical Research Institute have discovered that breast cancer cells that metastasize to the lung show a higher level of a specific protein. The protein, peroxiredoxin 2...
View ArticleBiomarkers found for chemotherapy resistance in breast cancer
Researchers at the University of Hull have identified biomarkers which could help to predict resistance to chemotherapy in breast cancer patients. Potential biomarkers associated with resistance to...
View ArticleKinase test has potential to combat drug-resistant cancers
A team at the University of North Carolina introduced the first broad-based test for activation of protein kinases, allowing measurement of the mechanism behind drug-resistant cancer and prediction of...
View ArticleBoston University researchers identify key regulator of inflammatory response
Researchers at Boston University School of Medicine have identified a gene that plays a key role in regulating inflammatory response and homeostasis. This could help lead to the development of...
View ArticleProtein's function in cell nucleus contributes to understanding of cancer...
Researchers at the Hospital de Mar Research Institute have discovered that the protein LOXL2 has a function within the cell nucleus. A newly-discovered chemical reaction of this protein on histone H3...
View ArticleDNA repair pathway information could predict chemotherapy response in ovarian...
Most advanced ovarian cancer patients undergo surgery to remove as much tumor as possible, and then undergo platinum-based chemotherapy. But predicting response to chemotherapy is difficult. In order...
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